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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ANAPC1 All Species: 24.24
Human Site: T1198 Identified Species: 48.48
UniProt: Q9H1A4 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9H1A4 NP_073153.1 1944 216500 T1198 L N I H D Y L T K G H E M T S
Chimpanzee Pan troglodytes XP_515601 1394 155989 N698 T E L D V P H N V Q V A A V V
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_532958 1943 216470 T1197 L N I H D Y L T K G H E M T S
Cat Felis silvestris
Mouse Mus musculus P53995 1944 216068 T1198 L N I H D Y L T K G H E M T S
Rat Rattus norvegicus NP_001101241 1944 216060 T1198 L N I H D Y L T K G H E M T S
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus XP_419303 1945 216100 T1200 L N I H D Y L T K G H E M T S
Frog Xenopus laevis
Zebra Danio Brachydanio rerio XP_001921168 1979 220132 T1245 L N I H D Y L T K G H E M T S
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_573025 2030 227256 V1271 M S V Y K Y L V K C D E M T N
Honey Bee Apis mellifera XP_001122449 1939 218025 V1188 F S M Y E Y L V E C H E A T S
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_001202400 910 100394 S214 S S L L P P T S T E L D V P H
Poplar Tree Populus trichocarpa XP_002312165 1929 212815 A1219 G Q M M D G T A V N V D V T A
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana NP_196175 1678 186257 L982 L Q G Y L H V L N L S D I Y Q
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 71.5 N.A. 97.3 N.A. 92.1 92.9 N.A. N.A. 81.7 N.A. 66 N.A. 33.6 38 N.A. 25.2
Protein Similarity: 100 71.5 N.A. 98.5 N.A. 96 96.5 N.A. N.A. 90.2 N.A. 79 N.A. 52.2 59.1 N.A. 33.8
P-Site Identity: 100 0 N.A. 100 N.A. 100 100 N.A. N.A. 100 N.A. 100 N.A. 40 40 N.A. 0
P-Site Similarity: 100 6.6 N.A. 100 N.A. 100 100 N.A. N.A. 100 N.A. 100 N.A. 73.3 73.3 N.A. 33.3
Percent
Protein Identity: 28.5 N.A. N.A. 27.2 N.A. N.A.
Protein Similarity: 47 N.A. N.A. 45.8 N.A. N.A.
P-Site Identity: 13.3 N.A. N.A. 6.6 N.A. N.A.
P-Site Similarity: 40 N.A. N.A. 40 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 9 0 0 0 9 17 0 9 % A
% Cys: 0 0 0 0 0 0 0 0 0 17 0 0 0 0 0 % C
% Asp: 0 0 0 9 59 0 0 0 0 0 9 25 0 0 0 % D
% Glu: 0 9 0 0 9 0 0 0 9 9 0 67 0 0 0 % E
% Phe: 9 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 9 0 9 0 0 9 0 0 0 50 0 0 0 0 0 % G
% His: 0 0 0 50 0 9 9 0 0 0 59 0 0 0 9 % H
% Ile: 0 0 50 0 0 0 0 0 0 0 0 0 9 0 0 % I
% Lys: 0 0 0 0 9 0 0 0 59 0 0 0 0 0 0 % K
% Leu: 59 0 17 9 9 0 67 9 0 9 9 0 0 0 0 % L
% Met: 9 0 17 9 0 0 0 0 0 0 0 0 59 0 0 % M
% Asn: 0 50 0 0 0 0 0 9 9 9 0 0 0 0 9 % N
% Pro: 0 0 0 0 9 17 0 0 0 0 0 0 0 9 0 % P
% Gln: 0 17 0 0 0 0 0 0 0 9 0 0 0 0 9 % Q
% Arg: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % R
% Ser: 9 25 0 0 0 0 0 9 0 0 9 0 0 0 59 % S
% Thr: 9 0 0 0 0 0 17 50 9 0 0 0 0 75 0 % T
% Val: 0 0 9 0 9 0 9 17 17 0 17 0 17 9 9 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 25 0 67 0 0 0 0 0 0 0 9 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _